Griffin Discoveries
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Griffin Discoveries Employees in Amsterdam: 1 |
Company Profile
The company spun-out of VU University Amsterdam in 2009 and is based on over 30 years of GPCR research. At present the company works in close collaboration with the academic group and has obtained all intellectual property rights to its GPCR research programs.
Current in-house discovery is comprised of a selective histamine H3R antagonist and histamine H4R antagonist program. In addition to the development of selective antagonists, a series of compounds is being developed with a mixed histaminergic profile that combines histamine H1R and histamine H4R antagonism in a single non-imidazole molecule.
Science and Technologies or Services
Griffin Discoveries offers comprehensive in vitro profiling of compounds that allows for a better understanding of observed compound behavior in vivo. Compound profiles for ligand binding and receptor activation can be generated for all histamine receptors of human, mouse and rat. In addition, profiles can be generated for monkey, dog and guinea-pig histamine receptors upon special request.
Alliances
- VU University Amsterdam
Keywords
- Drug Discovery
- Histamine ligands
- Histamine receptor & other screening assays
